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I agree with Kdancy, a chassis swap is a massive a lot of work and plenty of people get burnt out on the project. I see that on all projects though, not necessarily just chassis swaps. Was just trying to provide an alternative route, wasn't attempting to lead anyone into a "forever project" as you said.
As you can see from the last two posts someone is giving you some bad advice. We have a lot of modified 30's/40's Hudson's running around with SBC and 10" ford rear ends. As a matter of fact, most of the hot rods on the road today use this combination. You need to get with some Hudson folks that have done this swap and take some notes. A regional or national meet would be the perfect place to do this--look one up in your area or join us in San Diego the last week of august and see your project under construction and in action.... We have a lot of Hudson's that attend during the process.
All the above advice is great but no one has asked you what you want to do with the car. What do you want to use the car for? Cruising around with stretches longer that 30 min on the freeway at speeds above 60mph...... go the modification route, new engine and drive train. You will be happier. If you are cruising around town go stock. I have a 37 straight 8 and there is no way it can do freeway speeds without blowing up (no overdrive). I have a 46 pickup that I added and overdrive and tall tires to. It will go 60 for short periods of time but is not real happy. 50 - 55 is much more to its liking. So really consider what you are going to use the car for. I have a 53 hornet with a stroked 308. It loves to go fast all day long...... The vintage coach guys got it up to 97 the other day while tuning it and I think there was more left in it. It really pulls but it also has a triple weber setup.